Immune-Epithelial Crosstalk in Inflammatory Bowel Diseases and Mucosal Wound Healing

• Main Author: Britta Siegmund (auth)
• Other Authors: Moritz Leppkes (auth), Christoph Becker (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2018
• Series: Frontiers Research Topics
• Subjects: Medicine; lymphocytes; inflammatory bowel diseases; immune system; intestinal epithelium; mucosal immunity
• Online Access: DOAB: download the publication; DOAB: description of the publication

80% of the bodies' immune cells are harbored within the intestine. They are only separated from 1014 microorganisms by a single layer of intestinal epithelial cells and a secreted superficial mucus layer. Therefore, the intestinal epithelial surface represents a main frontier in host defense. P...