Ion Channel Trafficking and Cardiac Arrhythmias
A well-adjusted expression of cardiac ion channels at the sarcolemma is of crucial importance for normal action potential formation and thus cardiac function. The cellular processes that transport channel proteins from the endoplasmic reticulum towards specified regions on the sarcolemmal membrane,...
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| Other Authors: | , , |
| Format: | Electronic Book Chapter |
| Language: | English |
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Frontiers Media SA
2018
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| Series: | Frontiers Research Topics
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| Subjects: | |
| Online Access: | DOAB: download the publication DOAB: description of the publication |
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| 072 | 7 | |a MFG |2 bicssc | |
| 100 | 1 | |a Marcel A.G. van der Heyden |4 auth | |
| 700 | 1 | |a Brian P. Delisle |4 auth | |
| 700 | 1 | |a Hugues Abriel |4 auth | |
| 700 | 1 | |a Baoxin Li |4 auth | |
| 245 | 1 | 0 | |a Ion Channel Trafficking and Cardiac Arrhythmias |
| 260 | |b Frontiers Media SA |c 2018 | ||
| 300 | |a 1 electronic resource (123 p.) | ||
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| 490 | 1 | |a Frontiers Research Topics | |
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| 520 | |a A well-adjusted expression of cardiac ion channels at the sarcolemma is of crucial importance for normal action potential formation and thus cardiac function. The cellular processes that transport channel proteins from the endoplasmic reticulum towards specified regions on the sarcolemmal membrane, and subsequently take them from the plasma membrane to the protein degradation machinery are commonly known as trafficking. The research field recognizes that aberrant channel trafficking stands at the basis of many congenital and acquired arrhythmias. The collection of papers in this eBook provides state-of-the-art insight into the world of ion channel trafficking research. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by/4.0/ |2 cc |4 https://creativecommons.org/licenses/by/4.0/ | ||
| 546 | |a English | ||
| 650 | 7 | |a Physiology |2 bicssc | |
| 653 | |a Kv11.1 channels | ||
| 653 | |a Connexin43 (Cx43) | ||
| 653 | |a ion channel | ||
| 653 | |a arrhythmia | ||
| 653 | |a TRPM4 channel | ||
| 653 | |a Glycosylation | ||
| 653 | |a NaV1.5 channels | ||
| 653 | |a Kir2.1 channels | ||
| 653 | |a trafficking | ||
| 653 | |a Autophagy | ||
| 653 | |a Protein complexes | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://www.frontiersin.org/research-topics/5514/ion-channel-trafficking-and-cardiac-arrhythmias |7 0 |z DOAB: download the publication |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/50657 |7 0 |z DOAB: description of the publication |