Isolation and Structure Elucidation of Bioactive Compounds (Dedicated to the memory of the late Professor Charles D. Hufford)

• Main Author: Ilias, Muhammad (auth)
• Other Authors: Cantrell, Charles (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Subjects: Chemistry; Prosopis glandulosa; n/a; pentalogin; vasculogenesis; Cryptococcus neoformans; analgesic; diterpenes; muscadine; anti-leishmanial activity; Il-8; antioxidant activity; cryptococcosis; liver activity; antimicrobial resistance; monoamine oxidase-B; cytotoxic activity; monoamine oxidase-A; gastro-resistant; maleimides; Turnera diffusa; Cochlospermaceae; fusidic acid; jenipapo; polyketide; DNA barcoding; microparticles; antimalarial activity; insecticidal activity; aldose reductase inhibitor; Baccharis; antitrypanosomal activity; microbial transformation; coumarinolignans; methicillin resistant Staphylococcus aureus (MRSA); multi-drug resistant (MDR); channel catfish; carotenoids; dietary supplement; (E)-8(17); cardiomyogenesis; Xylariaceae; plant pathogenic and endophytic fungi; antipyretic; chromone; acacetin 7-methyl ether; inflammation; endophytic fungi; anti-inflammatory; acacetin; acylphloroglucinol; Arthrinium sp.; HPLC; amphotericin B; molecular dynamics; Cochlospermum vitifolium; lignans; augustine N-oxide; NF-?B; C-26-oxidation; isoxanthohumol; Cunninghamella echinulata; buphanisine N-oxide; Stevia rebaudiana; Torreya taxifolia; pyranoanthocyanin; Crinum amabile; antibacterial; sterols; Flavobacterium columnare; sesterterpene; isolation and elucidation; Jatropha pelargoniifolia; Rubiaceae; iNOS; Mitracarpus scaber Zucc.; obesity; neurological disorder; stilbenes; hop prenylflavanone; columnaris disease; zerumbol; molecular docking; phlorogluciniol; iso-stevioside X-ray structure; Zingiber monatnum; flavonoids; factor X; GC/MS; flavonoids glycosides; SAR; Leishmania donovani; terpenes; 13(S)-hydroxyatisenoic acid derivative; rebaudioside A isomers; MS/MS; malaria; HPLC-ESI-IT-MS/MS; natural products; Morus alba L.; biological activities; pancreatic cancer; thrombosis; prosopilosidine; Litsea cubeba; Nemania; HepG2; C-27-oxidation; resveratrol; cytotoxicity; 12-labdadiene-15; alkaloids; aromatic compounds; neuroprotective agent; diterpene glycosides; fluconazole; phytotoxicity; 16-dial; microscopy; cytochalasins; factor VII; herbal medicine
• Online Access: DOAB: download the publication; DOAB: description of the publication

We are very pleased to introduce the Book Version of our Special Issue in Molecules dedicated to the memory of the late Professor Dr. Charles D. Hufford. The issue has been a huge success, with 22 full-length peer-reviewed papers and a tribute by Professor Alice M.Clark. Authors, reviewers, and collaborators from many countries across the worldhave contributed to this endeavour, and we are truly grateful to all. This Special Issue isrepresentative of the broad impact that “Charlie” had on the field of bioactive naturalproducts. This Special Issue comprises papers from Professor Hufford’s former students,colleagues, and collaborators throughout the world who have utilized a wide array ofstate-of-the-art techniques to examine diverse natural sources to isolate and identify avariety of natural products with a wide spectrum of biological activities, including somenew microbial transformations and insights into bioactive molecules. Many new bioactive compounds are described and reported here for the first time. Bioactivities reportedinclude cytotoxicity, antimicrobial activity, anti-inflammatory activity, antileishmanialactivity, antitrypanosomal activity, antimalarial activity, analgesic activity, and beneficialliver activities, just to name a few. This Special Issue will undoubtedly have a lasting impact on the field of bioactive natural products, as exemplified by the career of Dr. Hufford.Lastly, without the timely and outstanding contributions from all of you, this Special Issue would not have been possible. We thank you all very much for your contributions and your time devoted to this Special Issue in memory of a special person. Finally, we express ourgratitude and thanks to the journal Molecules and their excellent team of expert reviewers for giving us the support and opportunity to make this Special Issue a huge success!