M1/M2 Macrophages: The Arginine Fork in the Road to Health and Disease

• Main Author: Charles Dudley Mills (auth)
• Other Authors: Laurel L Lenz (auth), Klaus Ley (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Medicine; Infection; wound; innate immunity; M1; M2; Atherosclerosis; macrophage; Cancer
• Online Access: DOAB: download the publication; DOAB: description of the publication

Macrophages have unique and diverse functions necessary for survival. And, in humans (and other species), they are the most abundant leukocytes in tissues. The Innate functions of macrophages that are best known are their unusual ability to either "Kill" or "Repair". Since killin...