Mechanisms of Innate Neuroprotection
As clinical trials of pharmacological neuroprotective strategies in stroke have been disappointing, attention has turned to the brain's own endogenous strategies for neuroprotection. Two endogenous mechanisms have been recently characterized, ischemic preconditioning and ischemic postconditioni...
Guardado en:
| Autor principal: | |
|---|---|
| Formato: | Electrónico Capítulo de libro |
| Lenguaje: | inglés |
| Publicado: |
Frontiers Media SA
2016
|
| Colección: | Frontiers Research Topics
|
| Materias: | |
| Acceso en línea: | DOAB: download the publication DOAB: description of the publication |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | As clinical trials of pharmacological neuroprotective strategies in stroke have been disappointing, attention has turned to the brain's own endogenous strategies for neuroprotection. Two endogenous mechanisms have been recently characterized, ischemic preconditioning and ischemic postconditioning. In the present topic newly characterized mechanisms involved in preconditioning- and postconditioning- neuroprotection will be discussed. The understanding of the mechanisms involved in the neuroprotective pathways induced by preconditioning and postconditioning will be clinically relevant for identifying new druggable target for neurodegenerative disorder therapy. Furthermore, the importance of these neuroprotective strategies resides in that it might be easily translatable into clinical practice. Therefore, the data presented here will highlight the capacity of ischemic preconditioning and postconditioning to be of benefit to humans. |
|---|---|
| Descripción Física: | 1 electronic resource (138 p.) |
| ISBN: | 978-2-88919-929-7 9782889199297 |
| Acceso: | Open Access |