Mechanisms of Mitotic Chromosome Segregation

This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. Experts in the field treat several important aspects of this subject: (1) the history of research on mitotic mechanisms, to serve as a background...

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Bibliographic Details
Main Author: J. Richard McIntosh (auth)
Format: Electronic Book Chapter
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2017
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520 |a This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. Experts in the field treat several important aspects of this subject: (1) the history of research on mitotic mechanisms, to serve as a background; (2) assembly of the mitotic spindle; (3) Kinetochore assembly and function; (4) the mechanisms of chromosome congression to the metaphase plate; (5) the spindle assembly checkpoint; (6) mechanisms to avoid and correct erroneous chromosome attachments to the spindle; (7) a molecular perspective on spindle assembly in land plants; (8) chromosome segregation in anaphase A; (9) spindle elongation in anaphase B; and (10) the consequences of errors in chromosome segregation. Each chapter provides the reader with a comprehensive and accurate picture of current research in a form that is both readable and authoritative. The volume is suitable for scholars in this and related fields and for teaching at an advanced level. 
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546 |a English 
650 7 |a Biology, life sciences  |2 bicssc 
653 |a genome stability 
653 |a Trisomies 
653 |a microtubule dynamics 
653 |a Checkpoints 
653 |a Inheritance 
653 |a Cell division 
653 |a centrosome 
653 |a Down Syndrome 
653 |a Cell motility 
653 |a Cell regulation 
653 |a chromosome segregation 
653 |a Microtubules 
653 |a Cell cycle 
653 |a kinetochore 
653 |a Cytoskeleton 
653 |a Cell reproduction 
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