Metal Metabolism in Animals

Through evolution of life, animals have adapted to the ubiquitous presence of metals in the biosphere. They utilize the more frequent ones as essential constituents of their biochemical machinery. In fact, about 40% of all proteins present in animal cells are so-called metalloproteins. On the other...

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Bibliographic Details
Main Author: Reinhard Dallinger (Ed.) (auth)
Format: Electronic Book Chapter
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2018
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Online Access:DOAB: download the publication
DOAB: description of the publication
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520 |a Through evolution of life, animals have adapted to the ubiquitous presence of metals in the biosphere. They utilize the more frequent ones as essential constituents of their biochemical machinery. In fact, about 40% of all proteins present in animal cells are so-called metalloproteins. On the other hand, animals have invented regulatory and detoxifying mechanisms to protect themselves from critical concentrations of both essential and non-essential metal concentrations. Metallomics is a modern approach applying cellular, biochemical, molecular and analytical methods to investigate the relationships of metals in their cellular context. The present edition contains a number of original articles and reviews dealing with various aspects of metallomics in animals, published as Special Issues of the International Journal of Molecular Sciences in 2016 and 2017. The book addresses subjects such as metal definition in biology, metabolism of metals in invertebrate and vertebrate animals, metal detoxification and regulation strategies, supplementation of essential trace elements, metal behavior in pregnancy and embryonic development, as well as metal toxicology and emerging medical implications. 
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650 7 |a Biology, life sciences  |2 bicssc 
653 |a Allergy 
653 |a Protein Biochemistry 
653 |a Oxidative Stress 
653 |a Metalloprotein 
653 |a Homeostasis 
653 |a Metal Uptake 
653 |a Iron 
653 |a Metal 
653 |a Synthase 
653 |a Immunity 
653 |a Accumulation 
653 |a Model Organism 
653 |a Methylmercury 
653 |a Development 
653 |a Metal Toxicity 
653 |a Essential Trace Element 
653 |a Copper 
653 |a Protection 
653 |a Molecular Methods 
653 |a Metal Supplementation 
653 |a Binding Specificity 
653 |a Cadmium 
653 |a Transgenic Organisms 
653 |a T Cells 
653 |a Non-Essential Trace Element 
653 |a Animal Model 
653 |a Hypersensitivity 
653 |a Detoxification 
653 |a Tolerance 
653 |a Histology 
653 |a Palladium 
653 |a Metalloenzyme 
653 |a Stress 
653 |a Zinc 
653 |a Regulation 
653 |a Nickel 
653 |a Protein Disease 
653 |a Mercury 
653 |a Phytochelatin 
653 |a Metallothionein 
653 |a Apoptosis 
653 |a Cancer 
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856 4 0 |a www.oapen.org  |u https://directory.doabooks.org/handle/20.500.12854/53247  |7 0  |z DOAB: description of the publication