Micro- and Nanofluidics for Bionanoparticle Analysis

• Main Author: Zeng, Yong (auth)
• Other Authors: Cheng, Xuanhong (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Subjects: History of engineering & technology; n/a; magnetic field; microfluidic device; ballpoint pen printing; paper-based microfluidic device; online analysis; nanoporous membrane; dielectric film; digital microfluidic chip; HIV diagnostics; precipitation; optically induced dielectrophoresis (ODEP); digital microfluidic device; fluorescence; ferrofluids; cancer metastasis; flow focusing; image processing; electrowetting; light diffraction; lensfree; nanoparticle characterization; multi-step assay; cell isolation; biomarker detection; microparticles; conductive electrode; single particle analysis; plastic wrap; second-hand smoke; flow control; surface acoustic wave; droplet actuation; circulating tumour cells (CTCs); lipid nanoparticles; crop disease; cross-flow filtration; oxidized hollow mesoporous carbon nanosphere; microfluidic systems; 3-ethenylpyridine; microfluidic; microfluidics; COMSOL; plug flow mixer
• Online Access: DOAB: download the publication; DOAB: description of the publication

Bionanoparticles such as microorganisms and exosomes are recoganized as important targets for clinical applications, food safety, and environmental monitoring. Other nanoscale biological particles, includeing liposomes, micelles, and functionalized polymeric particles are widely used in nanomedicines. The recent deveopment of microfluidic and nanofluidic technologies has enabled the separation and anslysis of these species in a lab-on-a-chip platform, while there are still many challenges to address before these analytical tools can be adopted in practice. For example, the complex matrices within which these species reside in create a high background for their detection. Their small dimension and often low concentration demand creative strategies to amplify the sensing signal and enhance the detection speed. This Special Issue aims to recruit recent discoveries and developments of micro- and nanofluidic strategies for the processing and analysis of biological nanoparticles. The collection of papers will hopefully bring out more innovative ideas and fundamental insights to overcome the hurdles faced in the separation and detection of bionanoparticles.