Micro- and Nanostructured Microfluidic Devices for Localized Protein Immobilization and Other Biomedical Applications

Micro- and Nanostructured Microfluidic Devices for Localized Protein Immobilization and Other Biomedical Applications

A new immobilization method for the localized adsorption of proteins on thermoplastic surfaces is introduced. Artificial three-phase interfaces were realized by surface structuring to control the wetting behavior which lead to a preferred adsorption in these modified areas. Additionally, different f...

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Bibliographic Details
Main Author: Steidle, Nicole E. (auth)
Format: Electronic Book Chapter
Language:English
Published: KIT Scientific Publishing 2014
Series:Schriften des Instituts für Mikrostrukturtechnik am Karlsruher Institut für Technologie / Hrsg.: Institut für Mikrostrukturtechnik
Subjects:
Technology: general issues
KunststoffverarbeitungLab-on-a-Chip
Mikrofluidik
Microfabrication
Lab-on-a-Chip
Polymer processing
Mikrofertigung
Microfluidics
Online Access:DOAB: download the publication
DOAB: description of the publication
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Summary:A new immobilization method for the localized adsorption of proteins on thermoplastic surfaces is introduced. Artificial three-phase interfaces were realized by surface structuring to control the wetting behavior which lead to a preferred adsorption in these modified areas. Additionally, different fabrication methods were analyzed to determine mass fabrication capabilities. These fabrication methods also allowed the production of fully structured microchannels to tune the fluids behavior within.
Physical Description:1 electronic resource (IX, 138 p. p.)
ISBN:KSP/1000044095
9783731502975
Access:Open Access

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