Micro- and Nanostructured Microfluidic Devices for Localized Protein Immobilization and Other Biomedical Applications

• Main Author: Steidle, Nicole E. (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: KIT Scientific Publishing 2014
• Series: Schriften des Instituts für Mikrostrukturtechnik am Karlsruher Institut für Technologie / Hrsg.: Institut für Mikrostrukturtechnik
• Subjects: Technology: general issues; KunststoffverarbeitungLab-on-a-Chip; Mikrofluidik; Microfabrication; Lab-on-a-Chip; Polymer processing; Mikrofertigung; Microfluidics
• Online Access: DOAB: download the publication; DOAB: description of the publication

A new immobilization method for the localized adsorption of proteins on thermoplastic surfaces is introduced. Artificial three-phase interfaces were realized by surface structuring to control the wetting behavior which lead to a preferred adsorption in these modified areas. Additionally, different f...