MicroRNA as Biomarkers in Cancer Diagnostics and Therapy
This Special Issue celebrates the 25th anniversary of the discovery of the first microRNA. The size of the microRNome and complexity of animal body plans and organ systems suggests a role for microRNAs in cell fate determination and differentiation. More than 2000 sequences have been proposed to rep...
Saved in:
| Main Author: | |
|---|---|
| Format: | Electronic Book Chapter |
| Language: | English |
| Published: |
MDPI - Multidisciplinary Digital Publishing Institute
2019
|
| Subjects: | |
| Online Access: | DOAB: download the publication DOAB: description of the publication |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000naaaa2200000uu 4500 | ||
|---|---|---|---|
| 001 | doab_20_500_12854_53436 | ||
| 005 | 20210211 | ||
| 003 | oapen | ||
| 006 | m o d | ||
| 007 | cr|mn|---annan | ||
| 008 | 20210211s2019 xx |||||o ||| 0|eng d | ||
| 020 | |a books978-3-03921-250-7 | ||
| 020 | |a 9783039212491 | ||
| 020 | |a 9783039212507 | ||
| 040 | |a oapen |c oapen | ||
| 024 | 7 | |a 10.3390/books978-3-03921-250-7 |c doi | |
| 041 | 0 | |a eng | |
| 042 | |a dc | ||
| 072 | 7 | |a PS |2 bicssc | |
| 100 | 1 | |a Sempere, Lorenzo F. |4 auth | |
| 245 | 1 | 0 | |a MicroRNA as Biomarkers in Cancer Diagnostics and Therapy |
| 260 | |b MDPI - Multidisciplinary Digital Publishing Institute |c 2019 | ||
| 300 | |a 1 electronic resource (166 p.) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a This Special Issue celebrates the 25th anniversary of the discovery of the first microRNA. The size of the microRNome and complexity of animal body plans and organ systems suggests a role for microRNAs in cell fate determination and differentiation. More than 2000 sequences have been proposed to represent unique microRNA genes in humans, with an increasing number of mechanistic roles identified in developmental, physiological, and pathological processes. Thus, dysregulation of a few key microRNAs can have a profound global effect on the gene expression and molecular programs of a cell. This great potential for clinical intervention has captured the interest and imagination of researchers in many fields. However, very few fields have been as prolific as the field of cancer research. This Special Issue provides but a glimpse of the large body of literature of microRNA biology in cancer research, containing 4 original research studies and 4 review articles that focus on specific hematologic or solid tumors in disease. Collectively, these articles highlight state-of-the-art approaches and methodologies for microRNA detection in tissue, blood, and other body fluids in a range of biomarkers applications, from early cancer detection to prognosis and treatment response. The articles also address some of the challenges regarding clinical implementation. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by-nc-nd/4.0/ |2 cc |4 https://creativecommons.org/licenses/by-nc-nd/4.0/ | ||
| 546 | |a English | ||
| 650 | 7 | |a Biology, life sciences |2 bicssc | |
| 653 | |a leukemia | ||
| 653 | |a n/a | ||
| 653 | |a cell lines | ||
| 653 | |a hepatitis B virus | ||
| 653 | |a long non coding RNA | ||
| 653 | |a normalization of miRNA expression in RT-qPCR | ||
| 653 | |a children | ||
| 653 | |a colorectal | ||
| 653 | |a review | ||
| 653 | |a bevacizumab | ||
| 653 | |a tumor budding cells | ||
| 653 | |a oral cancer | ||
| 653 | |a liquid biopsy | ||
| 653 | |a hepatocellular carcinoma | ||
| 653 | |a small t-antigen | ||
| 653 | |a colorectal cancer | ||
| 653 | |a protein-miRNA complex | ||
| 653 | |a biomarkers | ||
| 653 | |a biomarker | ||
| 653 | |a interleukin-1? | ||
| 653 | |a tissue analysis | ||
| 653 | |a miRNAs | ||
| 653 | |a T-cell acute lymphoblastic leukemia (T-ALL) | ||
| 653 | |a leukoplakia | ||
| 653 | |a inflammation | ||
| 653 | |a exosomes | ||
| 653 | |a circulating free DNA | ||
| 653 | |a hepatitis C virus | ||
| 653 | |a miRNA | ||
| 653 | |a miR-21 | ||
| 653 | |a extracellular microRNA | ||
| 653 | |a endogenous controls | ||
| 653 | |a lymphoma | ||
| 653 | |a confocal slide scanning microscopy | ||
| 653 | |a early diagnosis | ||
| 653 | |a reference genes | ||
| 653 | |a large T-antigen | ||
| 653 | |a microRNA | ||
| 653 | |a miRNA (microRNA) | ||
| 653 | |a cancer | ||
| 653 | |a TNF-? | ||
| 653 | |a plasma | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://mdpi.com/books/pdfview/book/1461 |7 0 |z DOAB: download the publication |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/53436 |7 0 |z DOAB: description of the publication |