MicroRNA as Biomarkers in Cancer Diagnostics and Therapy

• Main Author: Sempere, Lorenzo F. (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Subjects: Biology, life sciences; leukemia; n/a; cell lines; hepatitis B virus; long non coding RNA; normalization of miRNA expression in RT-qPCR; children; colorectal; review; bevacizumab; tumor budding cells; oral cancer; liquid biopsy; hepatocellular carcinoma; small t-antigen; colorectal cancer; protein-miRNA complex; biomarkers; biomarker; interleukin-1?; tissue analysis; miRNAs; T-cell acute lymphoblastic leukemia (T-ALL); leukoplakia; inflammation; exosomes; circulating free DNA; hepatitis C virus; miRNA; miR-21; extracellular microRNA; endogenous controls; lymphoma; confocal slide scanning microscopy; early diagnosis; reference genes; large T-antigen; microRNA; miRNA (microRNA); cancer; TNF-?; plasma
• Online Access: DOAB: download the publication; DOAB: description of the publication

This Special Issue celebrates the 25th anniversary of the discovery of the first microRNA. The size of the microRNome and complexity of animal body plans and organ systems suggests a role for microRNAs in cell fate determination and differentiation. More than 2000 sequences have been proposed to rep...