MicroRNAs: Novel Biomarkers and Therapeutic Targets for Human Cancers
MicroRNAs (miRNAs) constitute a large family of small, approximately 20-22-nucleotide, non-coding RNAs that are involved in gene regulation, mainly at the post-transcriptional level. Multiple lines of evidence have indicated that miRNAs play important roles in the maintenance of biological homeostas...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Electronic Book Chapter |
| Language: | English |
| Published: |
MDPI - Multidisciplinary Digital Publishing Institute
2018
|
| Subjects: | |
| Online Access: | DOAB: download the publication DOAB: description of the publication |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000naaaa2200000uu 4500 | ||
|---|---|---|---|
| 001 | doab_20_500_12854_53438 | ||
| 005 | 20210211 | ||
| 003 | oapen | ||
| 006 | m o d | ||
| 007 | cr|mn|---annan | ||
| 008 | 20210211s2018 xx |||||o ||| 0|eng d | ||
| 020 | |a books978-3-03897-253-2 | ||
| 020 | |a 9783038972525 | ||
| 020 | |a 9783038972532 | ||
| 040 | |a oapen |c oapen | ||
| 024 | 7 | |a 10.3390/books978-3-03897-253-2 |c doi | |
| 041 | 0 | |a eng | |
| 042 | |a dc | ||
| 072 | 7 | |a M |2 bicssc | |
| 100 | 1 | |a Ryou-u Takahashi (Ed.) |4 auth | |
| 700 | 1 | |a Takahiro Ochiya (Ed.) |4 auth | |
| 245 | 1 | 0 | |a MicroRNAs: Novel Biomarkers and Therapeutic Targets for Human Cancers |
| 260 | |b MDPI - Multidisciplinary Digital Publishing Institute |c 2018 | ||
| 300 | |a 1 electronic resource (272 p.) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 506 | 0 | |a Open Access |2 star |f Unrestricted online access | |
| 520 | |a MicroRNAs (miRNAs) constitute a large family of small, approximately 20-22-nucleotide, non-coding RNAs that are involved in gene regulation, mainly at the post-transcriptional level. Multiple lines of evidence have indicated that miRNAs play important roles in the maintenance of biological homeostasis and that aberrant expression levels of miRNAs are involved in the onset of many diseases, including cancer. In various types of cancer, miRNAs play important roles in tumor initiation and development. Recently, miRNAs have been demonstrated to also be secreted via small endosome-derived vesicles called exosomes-which are derived from multiple cell types-including immunocytes and cancer cells. Exosomal miRNAs exert important functions in cell-to-cell communication and have been investigated as prognostic and diagnostic biomarkers. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by-nc-nd/4.0/ |2 cc |4 https://creativecommons.org/licenses/by-nc-nd/4.0/ | ||
| 546 | |a English | ||
| 650 | 7 | |a Medicine |2 bicssc | |
| 653 | |a tumor initiation and development | ||
| 653 | |a cancer therapy | ||
| 653 | |a circulating microRNA | ||
| 653 | |a microRNA | ||
| 653 | |a diagnosis | ||
| 653 | |a biomarker | ||
| 653 | |a exosome | ||
| 856 | 4 | 0 | |a www.oapen.org |u https://www.mdpi.com/books/pdfview/book/800 |7 0 |z DOAB: download the publication |
| 856 | 4 | 0 | |a www.oapen.org |u https://directory.doabooks.org/handle/20.500.12854/53438 |7 0 |z DOAB: description of the publication |