Mitochondria: Hubs of Cellular Signaling, Energetics and Redox Balance

• Main Author: Amadou K. S. Camara (auth)
• Other Authors: Miguel A. Aon (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2017
• Series: Frontiers Research Topics
• Subjects: Physiology; redox and energetic compartmentation; light- and anesthetics-induced cardioprotection; redox metabolism and signaling; hypertrophic and diabetic cardiomyopathies; skeletal-cardiac muscle and brain protection; ketone bodies; post-translational modifications; redox aging; lipid catabolism; necroptosis
• Online Access: DOAB: download the publication; DOAB: description of the publication

Poised at the convergence of most catabolic and anabolic pathways, mitochondria are the center of heterotrophic aerobic life, representing a hub in the overall metabolic network of cells. The energetic functions performed by mitochondria face the unavoidable redox hurdle of handling huge amounts of...