Mitochondrial Dysfunction in Ageing and Diseases

• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2016
• Subjects: neurodegenerative diseases; mitochondrial diseases; pain; metabolic diseases; Ageing; protein homeostasis; cell/retrograde signaling; immune system; cancer; therapies to counteract mitochondrial dysfunction; oxidative stress
• Online Access: DOAB: download the publication; DOAB: description of the publication

The past decade has witnessed an explosion of knowledge regarding how mitochondrial dysfunction may translate into ageing and disease phenotypes, as well as how it is modulated by genetic and lifestyle factors. Impairment of the mitochondria may be caused by mutations or deletions in nuclear or mito...