Molecular mechanisms for reprogramming hippocampal development and function by early-life stress

• Main Author: Mathias V. Schmidt (auth)
• Other Authors: Xiao-Dong Wang (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Neurosciences; development; molecular mechanism; early-life stress; plasticity; Hippocampus; psychiatric disorders
• Online Access: DOAB: download the publication; DOAB: description of the publication

The early postnatal period is a crucial stage for hippocampal development. During this critical period, the neonatal hippocampus is highly sensitive to the detrimental consequences of adverse environmental factors. Extensive clinical and preclinical evidence has shown that traumatic events early in...