Molecular mechanisms regulating cytotoxic lymphocyte development and function, and their associations to human diseases

Cytotoxic lymphocytes, comprised of NK cells and cytotoxic T cells, play a pivotal role in immune defense. By directed release of perforin-containing lytic granules, NK and cytotoxic T cells can eradicate pathogen-infected, tumorigenic, and otherwise stressed cells. By the virtue of cytokine and che...

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Bibliographic Details
Main Author: Konrad Krzewski (auth)
Other Authors: Yenan Bryceson (auth)
Format: Electronic Book Chapter
Language:English
Published: Frontiers Media SA 2015
Series:Frontiers Research Topics
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