Multiscale Modeling of the Ventricles: From Cellular Electrophysiology to Body Surface Electrocardiograms

This work is focused on different aspects within the loop of multiscale modeling:On the cellular level, effects of adrenergic regulation and the Long-QT syndrome have been investigated.On the organ level, a model for the excitation conduction system was developed and the role of electrophysiological...

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Detalhes bibliográficos
Autor principal: Keller, David Urs Josef (auth)
Formato: Recurso Electrónico Capítulo de Livro
Idioma:inglês
Publicado em: KIT Scientific Publishing 2011
Colecção:Karlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering
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Descrição
Resumo:This work is focused on different aspects within the loop of multiscale modeling:On the cellular level, effects of adrenergic regulation and the Long-QT syndrome have been investigated.On the organ level, a model for the excitation conduction system was developed and the role of electrophysiological heterogeneities was analyzed.On the torso level a dynamic model of a deforming heart was created and the effects of tissue conductivities on the solution of the forward problem were evaluated.
Descrição Física:1 electronic resource (XIII, 248 p. p.)
ISBN:KSP/1000023886
9783866447141
Acesso:Open Access