NK Cell Subsets in Health and Disease: New Developments

Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory...

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Gorde:
Xehetasun bibliografikoak
Egile nagusia: Emanuela Marcenaro (auth)
Beste egile batzuk: Luigi D. Notarangelo (auth), Jordan S. Orange (auth), Eric Vivier (auth)
Formatua: Baliabide elektronikoa Liburu kapitulua
Hizkuntza:ingelesa
Argitaratua: Frontiers Media SA 2017
Saila:Frontiers Research Topics
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DOAB: description of the publication
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Deskribapena
Gaia:Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.
Deskribapen fisikoa:1 electronic resource (243 p.)
ISBN:978-2-88945-350-4
9782889453504
Sartu:Open Access