Novel Therapeutic Targets and Emerging Treatments for Fibrosis

• Main Author: Timothy D. Hewitson (auth)
• Other Authors: Chrishan S. Samuel (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2018
• Series: Frontiers Research Topics
• Subjects: Pharmacology; treatment strategies; Fibrosis; pharmacology; collagen; fibrogenesis; therapeutic targets
• Online Access: DOAB: download the publication; DOAB: description of the publication

For decades we have known that the overgrowth, hardening and scarring of tissues (so-called fibrosis) represents the final common pathway and best histological predictor of disease progression in most organs. Fibrosis is the culmination of both excess extracellular matrix deposition due to ongoing o...