Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials

Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynam...

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Bibliographic Details
Main Author: Afonin, Kirill (auth)
Format: Electronic Book Chapter
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
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Online Access:DOAB: download the publication
DOAB: description of the publication
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520 |a Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynamically reacts to changes in the surrounding environment. It is now evident that artificially designed self-assembling RNAs, that can form programmable nanoparticles and supra-assemblies, will play an increasingly important part in a diverse range of applications, such as macromolecular therapies, drug delivery systems, biosensing, tissue engineering, programmable scaffolds for material organization, logic gates, and soft actuators, to name but a few. The current exciting Special Issue comprises research highlights, short communications, research articles, and reviews that all bring together the leading scientists who are exploring a wide range of the fundamental properties of RNA and DNA nanoassemblies suitable for biomedical applications. 
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653 |a ribozyme 
653 |a biological media 
653 |a RNA aptamers 
653 |a gene therapy 
653 |a biosensors 
653 |a viral vector 
653 |a ganciclovir 
653 |a RNA self-assembly 
653 |a RNA nanoparticle 
653 |a gene delivery 
653 |a riboswitch 
653 |a non-viral gene delivery 
653 |a NANPs 
653 |a silver nanoclusters 
653 |a small-angle neutron scattering 
653 |a contrast variation 
653 |a aptamers 
653 |a RNA logic 
653 |a fluorogenic RNA 
653 |a glioblastoma multiforme 
653 |a RNA interference 
653 |a nucleic acid nanoparticles 
653 |a immunostimulation 
653 |a aggregation 
653 |a small-angle X-ray scattering 
653 |a non-viral vector 
653 |a light-up aptamer 
653 |a nucleic acid therapeutic 
653 |a live-cell imaging 
653 |a DNA nanotechnology 
653 |a nucleic acid computing 
653 |a nanopores 
653 |a structural characterization 
653 |a siRNA 
653 |a suicide gene therapy 
653 |a nucleic acid nanoparticle 
653 |a cytosine rich sequences 
653 |a RNA nanotechnology 
653 |a logic gates 
653 |a serum 
653 |a conditional activation 
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