Obesity-induced inflammation and insulin resistance

• Main Author: Tsuguhito Ota (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2014
• Series: Frontiers Research Topics
• Subjects: pattern-recognition receptor; innate immunity; inflammation; Bariatric surgery; macrophage; Adipose Tissue; insulin resistance; obesity
• Online Access: DOAB: download the publication; DOAB: description of the publication

Immune response and metabolic regulation are highly integrated and this interface maintains a central homeostatic system, dysfunction of which can cause obesity-associated metabolic disorder such as type 2 diabetes, fatty liver disease and cardiovascular disease. Insulin resistance is an underlying...