Paradigm changes are required in HIV vaccine research

• Main Author: Marc H. V. Van Regenmortel (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Medicine; HIV tolerogenic vaccine; germline antibodies; SIV vaccine; Mucosal vaccine; Therapeutic vaccine; vaccine efficacy trials; neutralizing antibodies; structure-based reverse vaccinology; antibody polyspecificity; bacterial adjuvants
• Online Access: DOAB: download the publication; DOAB: description of the publication

In his 1962 book "The Structure of Scientific Revolutions", Thomas Kuhn famously argued that researchers in every field of scientific enquiry always operate under a set of presuppositions known as paradigms that are rarely explicitly stated. In the field of HIV vaccine research, several pr...