Pharmaceutical Crystals

• Main Author: Uekusa, Hidehiro (auth)
• Other Authors: Yonemochi, Etsuo (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Chemistry; crystal structure analysis; n/a; famotidine; solution crystallization; salt optimization; structure determination from powder diffraction data; Hirshfeld surface analysis; DFT; molecular docking study; melting diagram; dehydration; hygroscopicity; HBV; Benzodioxole; pharmaceutical crystals; 4-b]indol-4-one; pyrimidin-4(3H)-one; liquid assisted grinding; HOMO-LUMO; dissolution; cocrystal formation; Raman spectroscopy; carbamazepine; hydrogen bonding; 3; ondansetron; physicochemical properties; solubility; succinic acid; cocrystal; adefovir dipivoxil; hepatitis B; polymorphs; hydrogen-bond-acceptance ability; DFT study; Nitrofurantoin-4-dimethylaminopyridine (NF-DMAP) salt; photostability; on-line monitoring; 5-dihydro-4H-pyrimido[5; Imidazole; Semicarbazone; crystal habit; Crystal structure; solvent-mediated polymorphic transformation; ticagrelor; hydrate; pharmaceutical cocrystal; malonic acid; 1H-indole; reactivity descriptors; famoxadone; crystal structure; dicarboxylic acid; hydrogen bond; saccharin
• Online Access: DOAB: download the publication; DOAB: description of the publication

The crystalline state is the most commonly used essential solid active pharmaceutical ingredient (API). The characterization of pharmaceutical crystals encompasses many scientific disciplines, but the core is crystal structure analysis, which reveals the molecular structure of essential pharmaceutic...