Recent Progress in Understanding the Mechanism and Consequences of Retrotransposon Movement

• Main Author: David J. Garfinkel (Ed.) (auth)
• Other Authors: Katarzyna J. Purzycka (Ed.) (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2017
• Subjects: Biology, life sciences; Non-LTR retrotransposon; Integration; Human disease; Endogenous retrovirus; Reverse transcription; Host factors; Genome evolution; LTR retrotransposon
• Online Access: DOAB: download the publication; DOAB: description of the publication

Retrotransposons are present in essentially all eukaryotic genomes and come in two basic flavors: those that are bracketed by long terminal repeats (LTRs) and share a common ancestor with retroviruses, and non-LTR retrotransposons that have a distinct lineage and remain transpositionally active in h...