Regulation and targeting of enzymes mediating Parkinson's disease pathogenesis: focus on Parkinson's disease Kinases, GTPases and ATPases

• Main Author: Veerle Baekelandt (auth)
• Other Authors: Kirsten Harvey (auth), Jean-Marc Taymans (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2015
• Series: Frontiers Research Topics
• Subjects: Neurosciences; PINK1; Phosphorylation; ROCO proteins; LRRK2; ATP13A2; tau Proteins; alpha-Synuclein
• Online Access: DOAB: download the publication; DOAB: description of the publication

Understanding the molecular pathogenesis of Parkinson's disease (PD) is a priority in biomedical research and a pre-requisite to improve early disease diagnosis and ultimately to developing disease-modifying strategies. In the past decade and a half, geneticists have identified several genes th...