Regulation of Chemokine- Receptor Interactions and Functions

• Main Author: Martin J. Stone (Ed.) (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2018
• Subjects: Biochemistry; chemokine; expression; signaling; regulation; oligomerization; binding; inhibition; post-translational modification; glycosaminoglycan; chemokine receptor
• Online Access: DOAB: download the publication; DOAB: description of the publication

A hallmark of inflammation is the accumulation of leukocytes, which can serve to remove pathogens and necrotic tissue, but may also damage healthy tissue and exacerbate the inflammatory response. Our understanding of leukocyte recruitment in inflammation was revolutionized in the late 1980s by the d...