The role of arginase in endothelial dysfunction

• मुख्य लेखक: Rudolf Lucas (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2015
• श्रृंखला: Frontiers Research Topics
• विषय: Medicine; eNOS; Reactive Oxygen Species; L-citrulline; arginase inhibitors; vessel wall remodeling; impaired vasorelaxation; microvascular permeability
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

In recent years, an increasing number of manuscripts have been published addressing the deleterious role of arginase in endothelial dysfunction. ROS have been shown to play a crucial role in arginase activation, which in turn leads to eNOS dysfunction.