The Role of Mitochondria, Oxidative Stress and Altered Calcium Homeostasis in Amyotrophic Lateral Sclerosis: From Current Developments in the Laboratory to Clinical Treatments

• Yazar: Manoj Kumar Jaiswal (auth)
• Materyal Türü: Elektronik Kitap Bölümü
• Dil: İngilizce
• Baskı/Yayın Bilgisi: Frontiers Media SA 2017
• Seri Bilgileri: Frontiers Research Topics
• Konular: Neurosciences; Mitochondria; neurodegenerative disease; Ca2+ signaling; multidrug therapy; Amyotrophic lateral sclerosis (ALS); Superoxide dismutase 1 (SOD1); Motor neuron disease (MND); excitotoxicity; Riluzole; multifactorial disease
• Online Erişim: DOAB: download the publication; DOAB: description of the publication

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive, devastating and fatal disease characterized by selective loss of upper and lower motor neurons of the cerebral cortex, brainstem, spinal cord and muscle atrophy. In spite of many years of research, the pathogenesis of ALS is still not wel...