Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function

• Yazar: Michel Kranendonk (auth)
• Diğer Yazarlar: Wayne L. Backes (auth), Ulrich M. Zanger (auth), Amit V. Pandey (auth), Colin J. Henderson (auth), Yuji Ishii (auth)
• Materyal Türü: Elektronik Kitap Bölümü
• Dil: İngilizce
• Baskı/Yayın Bilgisi: Frontiers Media SA 2018
• Seri Bilgileri: Frontiers Research Topics
• Konular: Pharmacology; POR; Pharmacogenetics; UGT; Biocatalysis; UDP-glucuronosyltransferase; Cytochrome P450; Drug metabolism; Membrane-associated progesterone receptor; PXR; Steroids
• Online Erişim: DOAB: download the publication; DOAB: description of the publication

Genetic variations may change the structure and function of individual proteins as well as affect their interactions with other proteins and thereby impact metabolic processes dependent on protein-protein interactions. For example, cytochrome P450 proteins, which metabolize a vast array of drugs, st...