The Second Life of Natural Killer (NK) Cells

Natural Killer (NK) cells are innate lymphocytes, now recognized as members of a larger family of "Innate lymphoid cells" (ILCs). Both murine and human NK cells are well characterized effector cells with cytotoxic as well as cytokine production ability which mainly react in response to mic...

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Hoofdauteur: Joseph C. Sun (auth)
Andere auteurs: Marco Colonna (auth), Chiara Romagnani (auth)
Formaat: Elektronisch Hoofdstuk
Taal:Engels
Gepubliceerd in: Frontiers Media SA 2018
Reeks:Frontiers Research Topics
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Online toegang:DOAB: download the publication
DOAB: description of the publication
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520 |a Natural Killer (NK) cells are innate lymphocytes, now recognized as members of a larger family of "Innate lymphoid cells" (ILCs). Both murine and human NK cells are well characterized effector cells with cytotoxic as well as cytokine production ability which mainly react in response to microbial and cell stress stimuli, thus playing a central role in the defense against pathogen infection, in tumor surveillance and in regulating immune homeostasis. Despite these established concepts, our understanding of the complexity of NK cells, also in view of their developmental and functional relationship with other ILC subsets, is only recently emerging. This Research Topic highlights the recent advances in NK cell (and ILC) research in human and mouse from basic research to clinical applications. 
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653 |a natural killer cells 
653 |a ILC 
653 |a NK cells 
653 |a immune therapy 
653 |a viral infection 
653 |a NK cell education 
653 |a immunotherapy 
653 |a MHC-I 
653 |a cancer 
653 |a immune regulation 
653 |a adaptive immunity 
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