Synthetic and Biosynthetic Approaches to Marine Natural Products

• Main Author: Barbero, Asunción (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Medicine; antarctic-derived fungus; marine drugs analogues; antitumor; pallescensone; Haematococcus pluvialis; toluquinol; antiproliferative activity; astaxanthin; thymoquinone; alotamide; microalgae; tetrahydropyrans; isomicrocionin-3; hybrid polyketides; anticonvulsant; peptide/polyketide molecules; functional-analogues; Synechococcus sp. PCC 7942; natural compound analogues; LLC-PK1 cells; structural modification; relative structural determination; benzo[d]thiazol; Cladosporium sphaerospermum; hybrid PKS-NRPS; anticandidal activity; Octopus minor; dihydropallescensin 2; Candida albicans; Iso-Seq; biological activity; Octominin; pallescensin 2; pallescensin 1; stereoselective; synthetic analogues; psammaplin A; cyclogeranylsulfonylbenzene isomers; synthesis; smenamides; MM cell line; ?-ketoacyl ACP Synthase; antidepressant; marine natural products; marine hydroquinone; tetramic acid; asymmetric synthesis; acid mediated cyclization; stereoselective synthesis; GGPPS; furanosesquiterpenes; marine natural product; short chain fatty acids; antimicrobial peptides; lipase-mediated resolution
• Online Access: DOAB: download the publication; DOAB: description of the publication

Marine natural products containing a heterocyclic moiety in their structure are present in a wide variety of sponges, corals, algae, and fungi. Many of them show important biological activities such as cytotoxic properties against several cancer cell lines. Their challenging chemical structures have...