Synthetic DNA and RNA Programming

• Main Author: O'Donoghue, Patrick (auth)
• Other Authors: Heinemann, Ilka (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2019
• Subjects: Biology, life sciences; growth effect; lysine acetylation; Escherichia coli; posttranslational modification; class II aminoacyl-tRNA synthetase; amber stop codon suppression; genetic code expansion; yeasts; phosphoseryl-tRNA synthetase; M. jannaschii orthogonal pair; gene ontology; selenocysteine; genetic firewall; indirect tRNA aminoacylation; tRNA editing; unnatural nucleotides; reverse polymerization; RNA metabolism; genome editing; tRNA; tRNASer; alternative amino acid and nucleotide repertoires; biocontainment; fluorescent reporter; optogenetics; tRNASep; GluRS-like; genetic isolation; live cell imaging; alternative core cellular chemistries; fluorescence-based screen; phosphoinositide dependent kinase 1; synthetic biology; mistranslation; tRNA repair; synthetic life; CUG-Ser; unnatural amino acids; recombinant protein production; biopharmaceuticals; protein modification; functional conservation; branched-chain amino acids; alanyl-tRNA synthetase; release factor 1; cyclic peptides; AspRS; xenobiology; DNA delivery; gene overexpression; non-canonical amino acids; ASKA collection; protein kinase B; codon bias; microRNA quantification; anticodon; small molecule drug screening; mRNA display; genetic tools; protein engineering; misacylation; transfer RNA; Metschnikowia; genome synthesis; expanded genetic code; yeast two hybrid; orthogonal central dogma of molecular biology; microRNA; genome engineering
• Online Access: DOAB: download the publication; DOAB: description of the publication

Dear Colleagues, Synthetic biology is a broad and emerging discipline that capitalizes on recent advances in molecular biology, genetics, protein and RNA engineering and omics technologies. These technologies have transformed our ability to reveal the biology of the cell and the molecular basis of d...