Tumor Hypoxia: Impact in Tumorigenesis, Diagnosis, Prognosis and Therapeutics

• मुख्य लेखक: Christian R. Gomez (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2017
• श्रृंखला: Frontiers Research Topics
• विषय: Medicine; microenvironment; Stem Cells; hypoxia; stress; HIF; tumor; Leukemia; biomarkers; therapy; pH
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Hypoxic regions have been identified within tumors and its presence has been linked to malignant progression, metastasis, resistance to therapy, and poor clinical outcomes following treatment. Acute and chronic hypoxia are integral components of tumor microenvironment and conduce to metabolic adapta...