The unfolded protein response in virus infections

• मुख्य लेखक: Shiu-Wan Chan (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2015
• श्रृंखला: Frontiers Research Topics
• विषय: Microbiology (non-medical); ERAD; virus-host interaction; innate immunity; Gene Therapy; Pathogenesis; Endoplasmic Reticulum Stress; Unfolded Protein Response; Autophagy
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Unfolded protein response (UPR) is a cellular adaptive response for restoring endoplasmic reticulum (ER) homeostasis in response to ER stress. Perturbation of the UPR and failure to restore ER homeostasis inevitably leads to diseases. It has now become evident that perturbation of the UPR is the cau...