Why vaccines to HIV, HCV and Malaria have so far failed - Challenges to developing vaccines against immunoregulating pathogens

• Main Author: Magdalena Plebanski (auth)
• Other Authors: Eric J. Gowans (auth), Peter Smooker (auth), Shuo Li (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2016
• Series: Frontiers Research Topics
• Subjects: Medicine; influenza; HIV; Malaria; Infectious Disease; Genetics; Vaccine; HCV; immunology
• Online Access: DOAB: download the publication; DOAB: description of the publication

Despite continuous progress in the development of anti-viral and anti-bacterial/parasite drugs, the high cost of medicines and the potential for re-infection, especially in high risk groups, suggest that protective vaccines to some of the most dangerous persistent infections are still highly desirab...