Chapter: 'Analysis of Breast Cancer Cell Invasion Using an Organotypic Culture System' from book: 3D Cell Culture: Methods and Protocols

• मुख्य लेखक: Romana E. Ranftl (auth)
• अन्य लेखक: Fernando Calvo (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Springer Nature 2017
• श्रृंखला: Methods in Molecular Biology
• विषय: Oncology; Cancer-associated fibroblasts; Organotypic; Breast cancer; Metastasis; Invasion
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Metastasis is the main cause of cancer patient mortality. Local tumor invasion is a key step in metastatic dissemination whereby cancer cells dislodge from primary tumors, migrate through the peritumoral stroma and reach the circulation. This is a highly dynamic process occurring in three dimensions...