Amyotrophic Lateral Sclerosis Recent Advances and Therapeutic Challenges

• अन्य लेखक: Hegde, Muralidhar L. (संपादक)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: IntechOpen 2020
• विषय: Neurology & clinical neurophysiology
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

A flurry of recent research on the role of the RNA/DNA-binding proteins TDP-43 and FUS as well as a dozen other factors (e.g., C9ORF72 and profilin) has led to a new paradigm in our understanding of the pathobiology of the motor neuron disease, Amyotrophic Lateral Sclerosis (ALS). How these factors...