Immunosuppression
Our immune system is equipped with a series of defence mechanisms to recognise and respond to non-self molecules. Although essential for fighting off infections and preventing cancers, destructive immune responses pose a considerable challenge in autoinflammation and transplantation. Currently avail...
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Format: | Electronic Book Chapter |
Language: | English |
Published: |
IntechOpen
2020
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Subjects: | |
Online Access: | DOAB: download the publication DOAB: description of the publication |
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Summary: | Our immune system is equipped with a series of defence mechanisms to recognise and respond to non-self molecules. Although essential for fighting off infections and preventing cancers, destructive immune responses pose a considerable challenge in autoinflammation and transplantation. Currently available immunosuppressants help to control destructive immune responses. However, management of side-effects of lifelong immunosuppression, including cancer development and reduced survival, remain major problems. For this reason, an increasing amount of interest is directed towards the natural specific regulatory mechanism of the immune system. A better understanding of these mechanisms holds the key. This book presents a comprehensive overview of immune suppression in transplantation, cancer and viral infections. Chapters cover modulation of Treg as well as the new era of immunotherapy. |
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Physical Description: | 1 electronic resource (104 p.) |
ISBN: | intechopen.87403 9781839681240 9781839681233 9781839681257 |
Access: | Open Access |