Oxidative Stress in Diabetic Retinopathy

• Other Authors: Ortega, Ángel Luis (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Medicine; eicosanoids; oxidative stress; diabetic retinopathy; cyclooxygenase; lipoxygenase; Cytochrome P450; HDAC6; tubastatin A; retinal endothelial cells; retinal endothelial cell senescence; db/db mice; Cinnamomi Ramulus; Paeoniae Radix; CPA4-1; blood-retinal barrier; occludin; human retina; epiretinal membrane; internal limiting membrane; vitreoretinal surgery; macular hole; proliferative diabetic retinopathy; antioxidants; diabetes mellitus; free radicals; high-mobility group box 1 (HMGB1); inflammatory pathways; novel therapies; diabetic retinopathy (DR); inflammation; angiogenesis; extracellular vesicles; miRNA; biomarkers; apoptosis; fenofibrate; thioredoxin; hyperglycemia; astaxanthin; carotenoid; reactive oxygen species; photoreceptor cells; PI3K; Nrf2; eicosapentaenoic acid (EPA); docosahexaenoic acid (DHA); retinal pigment epithelium; antioxidant; ascorbic acid; retinal disease; vitamin D; GLP-1; superoxide dismutase; biomarkers of diabetic retinopathy; metabolic memory; tear film; aqueous humor; vitreous humor; mitochondria; redox; photoreceptor; glycation; aging; glyoxalase; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Summary

The combination of an increasing prevalence of diabetes and the aging of populations enables the appearance of a greater number of associated complications such as diabetic retinopathy. Diabetic retinopathy is the leading cause of preventable vision loss in working-age adults. The objective of this Special Issue is to highlight the existing evidence regarding the relationship between oxidative stress and low-grade chronic inflammation induced by hyperglycemia with the development and progression of diabetic retinopathy, with an emphasis on the importance of early diagnosis and the use of antioxidant and anti-inflammatory approaches to prevent or delay the harmful effects of diabetes on retinal tissue.

Physical Description

1 electronic resource (322 p.)

ISBN

books978-3-0365-0449-0
9783036504483
9783036504490

Access

Open Access