Oxidative Stress in Diabetic Retinopathy

The combination of an increasing prevalence of diabetes and the aging of populations enables the appearance of a greater number of associated complications such as diabetic retinopathy. Diabetic retinopathy is the leading cause of preventable vision loss in working-age adults. The objective of this...

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Other Authors: Ortega, Ángel Luis (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
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520 |a The combination of an increasing prevalence of diabetes and the aging of populations enables the appearance of a greater number of associated complications such as diabetic retinopathy. Diabetic retinopathy is the leading cause of preventable vision loss in working-age adults. The objective of this Special Issue is to highlight the existing evidence regarding the relationship between oxidative stress and low-grade chronic inflammation induced by hyperglycemia with the development and progression of diabetic retinopathy, with an emphasis on the importance of early diagnosis and the use of antioxidant and anti-inflammatory approaches to prevent or delay the harmful effects of diabetes on retinal tissue. 
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653 |a eicosanoids 
653 |a oxidative stress 
653 |a diabetic retinopathy 
653 |a cyclooxygenase 
653 |a lipoxygenase 
653 |a Cytochrome P450 
653 |a HDAC6 
653 |a tubastatin A 
653 |a retinal endothelial cells 
653 |a retinal endothelial cell senescence 
653 |a db/db mice 
653 |a Cinnamomi Ramulus 
653 |a Paeoniae Radix 
653 |a CPA4-1 
653 |a blood-retinal barrier 
653 |a occludin 
653 |a human retina 
653 |a epiretinal membrane 
653 |a internal limiting membrane 
653 |a vitreoretinal surgery 
653 |a macular hole 
653 |a proliferative diabetic retinopathy 
653 |a antioxidants 
653 |a diabetes mellitus 
653 |a free radicals 
653 |a high-mobility group box 1 (HMGB1) 
653 |a inflammatory pathways 
653 |a novel therapies 
653 |a diabetic retinopathy (DR) 
653 |a inflammation 
653 |a angiogenesis 
653 |a extracellular vesicles 
653 |a miRNA 
653 |a biomarkers 
653 |a apoptosis 
653 |a fenofibrate 
653 |a thioredoxin 
653 |a hyperglycemia 
653 |a astaxanthin 
653 |a carotenoid 
653 |a reactive oxygen species 
653 |a photoreceptor cells 
653 |a PI3K 
653 |a Nrf2 
653 |a eicosapentaenoic acid (EPA) 
653 |a docosahexaenoic acid (DHA) 
653 |a retinal pigment epithelium 
653 |a antioxidant 
653 |a ascorbic acid 
653 |a retinal disease 
653 |a vitamin D 
653 |a GLP-1 
653 |a superoxide dismutase 
653 |a biomarkers of diabetic retinopathy 
653 |a metabolic memory 
653 |a tear film 
653 |a aqueous humor 
653 |a vitreous humor 
653 |a mitochondria 
653 |a redox 
653 |a photoreceptor 
653 |a glycation 
653 |a aging 
653 |a glyoxalase 
653 |a n/a 
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