Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases

• Other Authors: Kwok, Hang Fai (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Humanities; Social interaction; DAPK1; SUMO; SENP; protein degradation; post-translational modification; amphibian Bowman-Birk inhibitor; Tat peptide; molecular cloning; antifungal; drug design; protease inhibitor; natural-based compound; anticancer therapy; lung cancer; survivin; apoptosis; STAT3; colorectal cancer; orientin; cell cycle arrest; Bcl-2 family proteins; Astragalus membranaceus; insulin; PI3K; AKT; PPARγ; PDX-1; Petasites japonicus; Asteraceae; lignan; anti-inflammation; NO; PGE2; iNOS; COX-2; molecular docking; peptides; kynurenines; binding affinity; μ-opioid receptor; pharmacophore; G-protein activation; fucoidan; PLGA; docetaxel; drug delivery system; anticancer therapy/cancer treatment; hIAPP; amyloidogenesis; insulin granules; endoplasmic reticulum; anionic lipids; F23R variant; β-sheet transitions; β-cell cytotoxicity; unfolded protein response; pomegranate; punicalagin; tannins; gingiva; fibroblasts; antioxidant; wound healing; branched-chain fatty acids; Conidiobolus heterosporus; peroxisome proliferator-activated receptor α; lipid metabolism; fatty acid oxidation; hepatocyte; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Natural-based biomolecules continuously play an important role in novel drug discovery for the treatment of chronic diseases. The development of natural peptide/protein-based, toxin-based, and antibody-based drugs can significantly improve the biomedical efficiency of disease-specific therapy. The f...