Molecular Psychiatry

• Other Authors: Rein, Theo (Editor), Fries, Gabriel R. (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Medicine; Mental health services; cardiovascular disease; cell adhesion molecules; immunology; inflammation; nervous system; schizophrenia; bipolar disorder; major depressive disorder; DNA methylation; response variability; antipsychotics; drug design; multi-target drugs; polypharmacology; multi-task learning; machine learning; biomarker discovery; psychiatry; serotonin; 5-HT 4 receptor; 5-HT4R; depression; mood disorder; expression; Alzheimer's disease; cognition; Parkinson's disease; forced swimming; Roman rat lines; stress; hippocampus; BDNF; trkB; PSA-NCAM; western blot; immunohistochemistry; general cognitive function; intelligence; GWAS; genetic correlation; childhood-onset schizophrenia (COS); induced pluripotent stem cell (iPSC); copy number variation (CNV); early neurodevelopment; neuronal differentiation; synapse; dendritic arborization; miRNAs; stress physiology; cytoskeleton; actin dynamics; DRR1; TU3A; FAM107A; acid sphingomyelinase; alcohol dependence; liver enzymes; sphingolipid metabolism; withdrawal; Hsp90; GR; stress response; steroid hormones; molecular chaperones; psychiatric disease; circadian rhythms; FKBP51; FKBP52; CyP40; PP5; DISC1; neurodevelopment; CRMP-2; proteomics; antidepressant treatment; HPA axis; gene expression; FKBP5; sleep; sleep EEG; biomarkers; antidepressants; cordance; gender; sex difference; antidepressant; rapid-acting; Ketamine; endocrinology; (2R,6R)-Hydroxynorketamine; electroconvulsive therapy; basic-helix-loop-helix; brain; coactivator; glucocorticoids; mineralocorticoid receptor knockout; transcription biology; dopaminergic gene polymorphisms; affective temperament; obesity; alpha-synuclein; SNCA; major depression; Hamilton Scale of Depression; chemokines; neuroinflammation; social defeat; Immune response; T cells; susceptibility; resilience; Treg cells; Th17 cells; behavior; PPARγ; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

The book highlights important aspects of Molecular Psychiatry, including molecular mechanisms, animal models, biomarkers, advanced methods, drugs and antidepressant response, as well as genetics and epigenetics. Molecular mechanisms are a vital part of the search for the biological basis of psychiat...