The Role of Selenium in Health and Disease

"Role of selenium in health and disease". This book contains ten articles covering recent advances in our understanding of the relationship between the essential micronutrient selenium and h...

Full description

Saved in:
Bibliographic Details
Other Authors: Méplan, Catherine (Editor), Hughes, David J. (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
Subjects:
Online Access:DOAB: download the publication
DOAB: description of the publication
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000naaaa2200000uu 4500
001 doab_20_500_12854_68786
005 20210501
003 oapen
006 m o d
007 cr|mn|---annan
008 20210501s2020 xx |||||o ||| 0|eng d
020 |a books978-3-03936-147-2 
020 |a 9783039361465 
020 |a 9783039361472 
040 |a oapen  |c oapen 
024 7 |a 10.3390/books978-3-03936-147-2  |c doi 
041 0 |a eng 
042 |a dc 
072 7 |a GP  |2 bicssc 
072 7 |a PS  |2 bicssc 
072 7 |a JFCV  |2 bicssc 
100 1 |a Méplan, Catherine  |4 edt 
700 1 |a Hughes, David J.  |4 edt 
700 1 |a Méplan, Catherine  |4 oth 
700 1 |a Hughes, David J.  |4 oth 
245 1 0 |a The Role of Selenium in Health and Disease 
260 |a Basel, Switzerland  |b MDPI - Multidisciplinary Digital Publishing Institute  |c 2020 
300 |a 1 electronic resource (170 p.) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a "Role of selenium in health and disease". This book contains ten articles covering recent advances in our understanding of the relationship between the essential micronutrient selenium and human health and disease. Taken together, these articles strengthen the evidence showing that selenium, as a constituent of selenoproteins, is central to biological stress responses and mechanisms commonly altered in most complex disorders. Relevant to public health concerns, this book also emphasizes the U-shaped dose-response relationship between selenium concentration and disease risk across diverse populations from Europe [articles 2,3,6], the Middle East and North Africa [9], and Taiwan [5]. This highlights the importance of personalized nutrition strategies targeted at individuals with increased risk of disease and low selenium intake. The mechanisms by which selenium status, selenoprotein expression, and inherited genetic variations in the selenium pathway interact to affect molecular pathways involved in disease development are explored in human cohorts [2,3,5-7], and in animal [4] and in vitro models [8]. Furthermore, some reports identified novel potential biomarkers of disease risk and prognosis within the selenium pathway that could further our understanding of many chronic diseases [2,3]. Overall, this book broadens our understanding of the role of selenium in chronic diseases, and provides new directions for future preventative approaches. 
540 |a Creative Commons  |f https://creativecommons.org/licenses/by/4.0/  |2 cc  |4 https://creativecommons.org/licenses/by/4.0/ 
546 |a English 
650 7 |a Research & information: general  |2 bicssc 
650 7 |a Biology, life sciences  |2 bicssc 
650 7 |a Food & society  |2 bicssc 
856 4 0 |a www.oapen.org  |u https://mdpi.com/books/pdfview/book/2552  |7 0  |z DOAB: download the publication 
856 4 0 |a www.oapen.org  |u https://directory.doabooks.org/handle/20.500.12854/68786  |7 0  |z DOAB: description of the publication