Mitochondria in Health and Diseases

• Other Authors: Javadov, Sabzali (Editor), Kozlov, Andrey V. (Editor), Camara, Amadou K.S (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Medicine; hypoglycemia; sodium dichloroacetate; pyruvate dehydrogenase kinase; pyruvate dehydrogenase; oxidative stress; neuron death; cholangiocellular carcinoma; mitochondria; energy metabolism; oxidative phosphorylation; 4-HNE; DRP1; ERK1/2; hippocampus; JNK; mitochondrial dynamics; PKA; protein phosphatases; TUNEL; DDE; high-fat diet; mitochondrial UCP2; ROS; antioxidant system; uncoupling protein; mitochondria: energy metabolism; lipid handling; fatty acid oxidation; potassium channel; reactive oxygen species; antioxidants; life span; aging; BKCa channels; pravastatin; gemfibrozil; liver; colon; mitochondrial function; cyclosporin A; mitochondria calcium buffering; mitochondria bioenergetics; mitochondria permeability transition pore; inorganic phosphate; hepatic fibrogenesis; HtrA2/Omi; reactive oxygen species stress; mitochondrial homeostasis; complex I (CI) deficiency; metabolome and proteome profiling; reactive oxygen species (ROS); respirasome assembly; electron tunneling (ET); perilipin 5; lipid droplet; H9c2 cardiomyoblasts; adenine nucleotide translocase; respiratory supercomplexes; ETC complexes; dentate granule cell; epilepsy; hyperforin; LONP1; neuroprotection; pilocarpine; seizure; siRNA; cardioprotection; mitochondrial permeability transition pores; mitochondrial connexin 43; cardiolipin; iron overload; hepcidin; transferrin; ferritin; ZIP; inflammation; mtDNA; mitochondrial dysfunction; muscle aging; physical performance; LHON; Siberian population; ancient mutation; specific genetic background; apoptosis; human amniotic membrane; mitochondrial cell death; BAX; BCL-2; tensile strength; mitochondrial gene expression; mtDNA transcription; mtRNA; post-transcriptional mtRNA processing; dsRNA; innate immunity; interferon response; amino acid neurotransmitter; cerebellar amino acid metabolism; hypoxia; 2-oxoglutarate dehydrogenase; tricarboxylic acid cycle; heart; cytoskeletal proteins; mitochondrial interactions; plectin; tubulin beta; signaling; GW9662; ischemia reperfusion injury; Langendorff; myocardial; pioglitazone; redox state; rosiglitazone; TZD; uncoupling; ADP/ATP carrier; KmADP; dextran; morphology; cardiomyocytes; telomere length; telomerase activity; development; regeneration; intranuclear mitochondria; healthy cells; electron and confocal microscopy; signaling pathways; ion homeostasis; human diseases
• Online Access: DOAB: download the publication; DOAB: description of the publication

Mitochondria are subcellular organelles evolved by the endosymbiosis of bacteria with eukaryotic cells. They are the main source of ATP in the cell and engaged in other aspects of cell metabolism and cell function, including the regulation of ion homeostasis, cell growth, redox status, and cell sign...