Matrix Metalloproteinases in Health and Disease

• Other Authors: Serra, Raffaele (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Humanities; Social interaction; hypersensitivity pneumonitis; metalloproteinases; genetic association; autoantibodies; MMP1; MMP2; SNPs; MMPs; TIMPs; CKD; peripheral vascular disease; biomarkers; proteinuria; eGFR; PAD.; NGAL; statins; arterial aneurysms; patients; collagenases; Crohn's disease; dental caries; mouth; periodontitis; matrix metalloproteinase-9; dialysis; on-line hemodiafiltration; high-flux dialysis; renal replacement therapy; kidney transplantation; Mac-1; CD147; leukocytes; platelets; adhesion; integrin αMβ2; matrix metalloproteinases; TIMP; synthetic inhibitors; RECK; matrix metalloproteinase; MAPKs; ischemia/reperfusion; eNOS; iNOS; inflammatory bowel disease; inflammation; NO; MMP-9; cGMP; Caco-2; matrix metalloproteinase-7; fibrosis; acute kidney injury; chronic kidney disease; apoptosis; health; disease
• Online Access: DOAB: download the publication; DOAB: description of the publication

Matrix metalloproteinases (MMPs) are members of an enzyme family and are critical for maintaining tissue allostasis. MMPs can catalyze normal turnover of the extracellular matrix (ECM) together with other metalloproteinases such as ADAM (a disintegrin and metalloproteinase) and ADAMTS (a disintegrin...