Antitumor and Anti-HIV Agents from Natural Products

• Other Authors: Nakagawa-Goto, Kyoko (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Research & information: general; natural phaeosphaeride A; antitumor activity; human tumor cell lines; HEF cell line; acute toxicity; aspidosperma-type; monoterpenoid indole alkaloids; antiproliferative activity; tubulin inhibitor; Bousigonia mekongensis; ursolic acid; DOTA; triterpenoids; cytotoxicity; diterpenoid alkaloids; human tumor cells; lipojesaconitine; delcosine; delpheline; kobusine; pseudokobusine; BRAF inhibitor; Mentha aquatica var. Kenting Water Mint; essential oil; chemoprevention; two-stage skin carcinogenesis; melanoma; curcumin analog; apoptosis; oxidative stress; drug-drug interaction; tamoxifen; taxol; cisplatin; Artemisia absinthium L.; antioxidants; total phenolic content; melanoma and breast cancer cell line; HaCaT cells; inflammation; breast cancer; cell cycle; flavonoids; reactive oxygen species; tumor suppression; antiretroviral agents; anti-HIV; marine metabolites; natural products; drug development; Ivalin; Carpesium divaricatum; hepatocellular carcinoma; mitochondria-mediated apoptosis; NF-κB; Hernandia nymphaeifolia; butanolides; lignan glycosides; coumarins; antiangiogenic; cancer; natural agents; chemistry; medicine; cancer stem cell; cervical cancer; pterostilbene; resveratrol; caffeic acid; cancer multidrug resistance; P-glycoprotein; phenolic acid; oxypeucedanin; Angelica dahurica; antiproliferation; G2/M phase cell cycle arrest; p53; SK-Hep-1; hepatoma cells; allyl isothiocyanate; benzyl isothiocyanate; sulforaphane; phenethyl isothiocyanate; bladder cancer; quercetin; oral squamous cell carcinoma cells; metastasis; cell cycle arrest; epithelial-to-mesenchymal transition; matrix metalloproteinase; transforming growth factor-β1; β-lapachone
• Online Access: DOAB: download the publication; DOAB: description of the publication

Cancer is the second leading cause of death worldwide, and was accountable for an estimated 9.6 million deaths in 2018. Nowadays, about 1 in 6 deaths in the world is due to cancer. Another major global public health issue is HIV. Over 70 million people have been infected with the HIV virus and about...