Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment

• Other Authors: Ferraris, Davide Maria (Editor), Miggiano, Riccardo (Editor), Rizzi, Menico (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Research & information: general; Biology, life sciences; Mycobacterium tuberculosis; line probe assay; second-line drugs; drug resistance; XDR-TB; MDR-TB; omics analysis; TB treatment; system analysis; Beijing B0/W148; Mycobacterium smegmatis; imidazo[1,2-b][1,2,4,5]tetrazine; MmpS5-MmpL5; efflux; drug discovery; tuberculosis; immune activation; HLA-DR; CD38; treatment response; Mycobacterium; macrophage; apoptosis; effector; cytokine; microRNA; Beijing genotype; Central Asia Outbreak; murine infection model; Virulence; pre-XDR-TB; Mycobacterium avium; unique metabolic pathways; subtractive genomics; drug target; uncharacterized proteins; BM-MSCs; Mtb; bone-homing; stem cell niche; latent tuberculosis; relapse; liposomes; M. tuberculosis; host-pathogen interactions; immune response; antitubercular drug discovery; antitubercular treatments; IL-18; IL-18BP; IL-18R; gene expression
• Online Access: DOAB: download the publication; DOAB: description of the publication

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Heal...