Arteriogenesis and Therapeutic Neovascularization

• Other Authors: Deindl, Elisabeth (Editor), Quax, Paul (Editor), Waltenberger, Johannes (Editor), Schmitz-Rixen, Thomas (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Medicine; factor VII activating protease; HABP2; VEGF; matrigel; neo-vascularization; hind limb ischemia; angiogenesis; arteriogenesis; ERK; endothelial cells; inflammation; macrophages; atherosclerosis; pericyte; rAAV; capillary; microRNA; isomiRs; epitranscriptome; neovascularization; A-to-I editing; m6A; RNA modifications; RNA methylation; lower extremity arterial disease; peripheral arterial disease; blood flow restriction; activity-based benefits; training effects; effect mechanism; hyperoxygenation; vein graft disease; vascular biology; spinal cord ischemia; paraplegia; aortic disease; TAAA; collateral network; paraspinous compartment; NO; NOTCH; innate immunity; mast cell; GH and eNOS; IGF-I; oxidative stress and arterial inflammation; vascular homeostasis; GHAS trial; collateral artery growth; SMC proliferation; potassium channel; KV1.3; KCa3.1; FGFR-1; Egr-1; PDFG-R; αSM-actin; TLR2/6; femoral artery ligation; blood flow recovery; collateral growth; VHL loss of function; microRNA-212/132; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

For many years, arteriogenesis, also called collateral formation, has been regarded as being a beneficial process to restore blood flow to distal tissues in occluded arteries. Therefore, it is frequently referred to in relation to therapeutic angiogenesis. Despite the big clinical potential and the...