Apheresis in Neurological Disorders

Apheresis in Neurological Disorders

Apheresis refers to an extracorporeal therapy which aims at removing pathological constituents from the patients' blood. Due to the development of new techniques as well as the discovery of novel autoimmune antibodies, it is increasingly recognized as an important therapeutic option for a varie...

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Bibliographic Details
Other Authors: Dorst, Johannes (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
Subjects:
Medicine
immunoadsorption
acute relapsing multiple sclerosis
plasma exchange
therapeutic apheresis
multiple sclerosis
optic neuritis
relapse
class IV
steroids
Alzheimer's clinical syndrome
dementia
autoantibodies
α1-Adrenergic receptor
Inflammatory neuropathy
chronic inflammatory demyelinating polyneuropathy
Guillain-Barré syndrome
paranodal antibodies
plasmapheresis
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
ß2 adrenoreceptor autoantibody
autoimmune encephalitis
limbic encephalitis
NMDAR (N-Methyl-D-Aspartat)
antibody
paraneoplastic
apheresis
therapeutic plasma exchange
neurological diseases
CRP
stroke
inflammation
n/a
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Summary:Apheresis refers to an extracorporeal therapy which aims at removing pathological constituents from the patients' blood. Due to the development of new techniques as well as the discovery of novel autoimmune antibodies, it is increasingly recognized as an important therapeutic option for a variety of autoimmune-mediated neurological disorders, including multiple sclerosis, myasthenia gravis, autoimmune encephalitis, Guillain-Barré syndrome, and many others. Therapeutic plasma exchange (TPE) constitutes the standard method of apheresis for most indications, while immunoadsorption (IA) offers a more specific, low-risk alternative. Both methods aim at removing auto-antibodies from the blood. Evidence for most neurological diseases is still low. Interestingly, more recent developments suggest that apheresis is not limited to the removal of autoantibodies but may also be useful in neurodegenerative and possibly even in acute vascular disorders.
Physical Description:1 electronic resource (174 p.)
ISBN:books978-3-03943-586-9
9783039435852
9783039435869
Access:Open Access

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